Database Overview
miR4ASD is an open-access, literature-based database that compiles human microRNAs (miRNAs) that were experimentally associated with Autism Spectrum Disorder (ASD). It includes manually curated data from peer-reviewed case-control studies, covering gene expression and genetic variant analysis. All miRNA names from different studies are standardized to miRBase version 22.1.
Key Features of miR4ASD:
Integrated Data
Integrates gene expression and miRNA profiling data from ASD-control studies.Tissue-Specific Patterns
Highlights tissue-specific expression patterns across brain and peripheral samples.Genetic Variants
Includes miRNAs with reported genetic variants — an underexplored area in ASD research.Research Enabler
Supports biomarker discovery, functional studies, and genetic research in ASD.Curation & Processing Workflow
Figure 1: Overview of the curation, standardization, and processing workflow implemented in the miR4ASD database.
Database Statistics & Visualizations
Click on any chart to open it in high resolution.
Eligible Studies
Pie chart showing the distribution and categorization of eligible studies included in the database.
Expression Studies by Tissue
Breakdown of expression studies grouped by the type of tissue analyzed (e.g., Blood, Brain, LCLs).
Genetic Studies by Variant
Distribution of genetic and other studies classified by the underlying variant types analyzed.
Top 10 Associated miRNAs
The top 10 human microRNAs ranked by the total number of independent studies reporting an association with ASD.
miRNAs in Common
Analysis of microRNAs common across different patient datasets or tissue groups.
Expression Studies Summary
Overview of specific miRNAs and their reported alterations in gene expression studies.
Genetic Studies Summary
Overview of specific miRNAs and their association with genetic variants in ASD datasets.| Precursor miRNA (hairpin) | Mature miRNA | Expression change (ASD vs. controls) | Tissue | Overall evidence | Number of studies (Upregulated) | Number of studies (Downregulated) | Total studies |
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| Precursor miRNA (hairpin) | Mature miRNA | Alteration | Study description |
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